Pharmacokinetic Demo Calculator

Loading Dose Calculation

Formula: Loading Dose = (Target Plasma Concentration × Volume of Distribution) / Bioavailability (F)

Target Plasma Concentration (mg/L):

Volume of Distribution (L):

Bioavailability (F, Enter as decimal):

Formula: Volume of Distribution (Vd) = (Clearance × Half-Life) / 0.693

Clearance (L/hr):

Half-life (hours):

Formula: Clearance = (Dose × Bioavailability (F)) / AUC

Dose (mg):

Area Under the Curve (mg/L/hr):

Bioavailability (F, Enter as decimal):

Formula: Maintenance Dose Rate = (Target Plasma Concentration × Clearance) / Bioavailability (F)

Target Plasma Concentration (mg/L):

Clearance (L/hr):

Bioavailability (F, Enter as decimal):

Formula: Half-Life = (0.693 × Volume of Distribution) / Clearance

Volume of Distribution (L):

Clearance (L/hr):